The compound Pycnogenol is made from the bark of a Mediterranean pine tree, which is primarily native to France. Pycnogenol is a strong antioxidant with anti-inflammatory effects and it is used to fight allergies, fever and asthma. Pycnogenol improves hydration and elasticity of the skin, and may slow down the aging process. It also helps with collagen production. It can activate your antioxidant defense and fight the free-radicals that may damage cells, tissue, organs and even DNA. It can also improve athletic endurance and female fertility and reduce attention-deficit disorder (ADHD) symptoms in children.