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The plant Ashwagandha contains many chemicals which might help in calming the brain, lowering blood pressure, reducing swelling and boosting the immune system. It’s classified as an adaptogen and is used for stress related conditions. Adaptogens help the body and the brain resist and counteract outside stressors. It’s good for managing anxiety, improving mood, reducing inflammation, as well as helping muscle strength and fertility. Some components in this plant, such as triethylene glycol, may promote sleepiness, which make it a good sleep aid. 

 

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42 Sources like nih.gov

A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults

https://pubmed.ncbi.nlm.nih.gov/23439798/

Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974

https://pubmed.ncbi.nlm.nih.gov/19718255/

A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera

https://pubmed.ncbi.nlm.nih.gov/21407960/

A RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED STUDY OFASHWAGANDHA ON GENERALIZED ANXIETY DISORDER

http://www.iamj.in/posts/images/upload/01.05.14_IAMJ.pdf

Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study

https://pubmed.ncbi.nlm.nih.gov/32021735/

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study

https://pubmed.ncbi.nlm.nih.gov/31728244/

An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study

https://pubmed.ncbi.nlm.nih.gov/31517876/

Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males

https://pubmed.ncbi.nlm.nih.gov/19501822/

Efficacy of Withania somnifera on seminal plasma metabolites of infertile males: a proton NMR study at 800 MHz

https://pubmed.ncbi.nlm.nih.gov/23796876/

Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial

https://pubmed.ncbi.nlm.nih.gov/26609282/

Withania somnifera Improves Semen Quality in Stress-Related Male Fertility

https://pubmed.ncbi.nlm.nih.gov/19789214/

A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males

https://pubmed.ncbi.nlm.nih.gov/30854916/

Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study

https://pubmed.ncbi.nlm.nih.gov/24371462/

Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adults

https://pubmed.ncbi.nlm.nih.gov/21170205/

Exploratory study to evaluate tolerability, safety, and activity of Ashwagandha (Withania somnifera) in healthy volunteers

https://pubmed.ncbi.nlm.nih.gov/23125505/

Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial

https://pubmed.ncbi.nlm.nih.gov/30463324/

Adjunctive Use of a Standardized Extract of Withania somnifera (Ashwagandha) to Treat Symptom Exacerbation in Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled Study

https://pubmed.ncbi.nlm.nih.gov/29995356/

Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial

https://pubmed.ncbi.nlm.nih.gov/27055824/

Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root

https://pubmed.ncbi.nlm.nih.gov/11116534/

Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study

https://pubmed.ncbi.nlm.nih.gov/24014929/

Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients

https://pubmed.ncbi.nlm.nih.gov/23142798/

Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial

https://pubmed.ncbi.nlm.nih.gov/28829155/

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study

https://pubmed.ncbi.nlm.nih.gov/26504795/

Evaluation of the efficacy of Withania somnifera (Ashwagandha) root extract in patients with obsessive-compulsive disorder: A randomized double-blind placebo-controlled trial

https://pubmed.ncbi.nlm.nih.gov/27515872/

A randomized, double blind placebo controlled study of efficacy and tolerability of Withaina somnifera extracts in knee joint pain

https://pubmed.ncbi.nlm.nih.gov/27647541/

Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists

https://pubmed.ncbi.nlm.nih.gov/23326093/

Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants

https://pubmed.ncbi.nlm.nih.gov/24497737/

Evaluation of antioxidant potential of Rasayana drugs in healthy human volunteers

https://pubmed.ncbi.nlm.nih.gov/25364199/

Randomized placebo-controlled adjunctive study of an extract of withania somnifera for cognitive dysfunction in bipolar disorder

https://pubmed.ncbi.nlm.nih.gov/24330893/

Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions

https://pubmed.ncbi.nlm.nih.gov/28471731/

In vivo effects of Ashwagandha (Withania somnifera) extract on the activation of lymphocytes

https://pubmed.ncbi.nlm.nih.gov/19388865/

Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults

https://pubmed.ncbi.nlm.nih.gov/26730141/

Comparative evaluation of the effects of Withania somnifera with pentoxifylline on the sperm parameters in idiopathic male infertility: A triple-blind randomised clinical trial

https://pubmed.ncbi.nlm.nih.gov/29770466/

Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review

https://pubmed.ncbi.nlm.nih.gov/10956379/

An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/

An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera)

https://pubmed.ncbi.nlm.nih.gov/25405876/

Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study

https://pubmed.ncbi.nlm.nih.gov/32818573/

Safety of Ashwagandha Root Extract: A Randomized, Placebo-Controlled, study in Healthy Volunteers

https://pubmed.ncbi.nlm.nih.gov/33338583/

An Alternative Treatment for Anxiety: A Systematic Review of Human Trial Results Reported for the Ayurvedic Herb Ashwagandha (Withania somnifera)

https://www.liebertpub.com/doi/full/10.1089/acm.2014.0177

Ashwagandha in brain disorders: A review of recent developments

https://www.sciencedirect.com/science/article/abs/pii/S0378874119339182

Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis

https://www.mdpi.com/2411-5142/6/1/20

Effects of Withania somnifera (Ashwagandha) on Stress and the Stress- Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia

https://www.ingentaconnect.com/content/ben/cn/2021/00000019/00000009/art00008
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